Elesha Turner, a student from Hastings, in East Sussex, was diagnosed with bone cancer after a holiday in Eqypt last June, The Express reported.
Doctors removed her femur, knee and the top of her tibia, before giving her a bionic leg.
"To think that I've gone from thinking I might lose my leg, to becoming a model, is just so surreal," she told The Express.
"When the doctors told me I had cancer, it was just a nightmare - I don't know anyone that's been affected by it before, so it was so scary.
Following rehabilitation, Elesha found an article about Models of Diversity in a magazine.
"My auntie and I thought it looked really interesting so I got in touch with Angel, the founder," she said.
"I'm going to be one of the faces of their disability campaign and I'm really excited - I can't wait to challenge people's perceptions," she told The Express.