The royal couple were on the last day of their Indian tour before they set off for Bhutan, when they were caught up in the disaster.
Catherine and William felt the tremors during their stay in Assam in north-east India, where they were visiting the Kaziranga National Park.
"As far as I know, tremors were felt across the region and everyone is okay," a royal spokesperson confirmed.
Watch highlights from their trip below. Post continues after the video!
Kensington Palace's official Twitter account have yet to comment on the event, but a Hello! royal reported has revealed, "The Duke and Duchess and their party are safe and sound as well as members of the press, who are staying in Guwahati, the largest city in Assam."
Meanwhile, British Deputy High Commissioner Scott Furssedonn-Wood, who was staying in the same jungle resort as the couple, recalled the event: "We felt the tremor very strongly, but all is fine."
Earlier on Wednesday the mum-of-two and her husband embarked on a safari adventure, where they had the chance to feed baby elephants and rhinos.
It was during this time the 34-year-old fondly spoke of her darling two kids Prince George and sweet Charlotte.
When village elders asked why they didn't bring the kids, Catherine said, "Because George is too naughty. He would be running all over the place. The next time we come we will definitely bring them!"
The future Queen also admitted she missed her kids, saying that the little girls dancing in the village reminded her of Princess Charlotte.
This is the first prolonged visit that she has spent apart from her young ones since she's given birth to them.
Despite the fact that Kate's mind was back home, it was clear the royal was loving her time in the natural environment.
The pretty brunette and her hubby-of-nearly-five-years sat on bamboo mats, where they learned about how the village was established in the 1970s, and how it now grows tea due to the local elephant and wildlife population.
"How do the local people view the elephants and rhinos, are they considered sacred?" William asked.
The 33-year-old was told the villagers "love" the elephants because they happily live alongside them.
Before Catherine and Wills set off for Bhutan, relive all the highlights from the royal India tour right here