Jason, who wrote and produced the movie, has described it as a "comedy drama touching on the battlelines between Australian rules and rugby league."
Isabel will step into the role of Brooke opposite Dan Ewing, who will portray her on-screen lover Chase.
Photos straight from the set of the movie shows that they looked very much at ease with each other during filming, with their chemistry jumping off the camera during steamy kissing scenes.
While Isabel is believed to be single, Dan split from his wife Marni last year and is currently dating So You Think You Can Dance alumni Kat Risteska – who he met on the Summer Bay set.
Kat revealed on Instagram that she has a role in her boyfriend's film, penning alongside a snap of her and Dan clinking their wine glasses, "Cheers to our first scenes together @chasingcometsofficial Massive thank you to @bigjasonstevens @beckjstevens @jasonperini for the opportunity to work on your incredible vision #chapril @_danewing"
Dan, 31, is clearly smitten with his leading lady.
Last week he shares a touching tribute to Kat on her birthday, saying, “Cheers to the big guy upstairs for blessing me with this aggressively kind, giving, savage, humble euro goddess I get to call my best friend and queen.”
Isabel, who will no doubt be bringing her Hollywood star-power to the film, admitted she couldn't be more excited to be returning to work after her one month hiatus in India.
“I am so appreciative for having such rich and varied experiences,” the 32-year-old told Sydney Confidential.
“Being able to spend the last month in India was very enriching and I loved it. I appreciate being able to live in LA but there’s nothing like being able to come home and work.”
Isabel has made a huge splash across the pond, starring in blockbusters like Transformers and Red Dawn.
But she admitted that there's nothing quite like being at home, working on local projects.
"I appreciate being able to live in LA but there's nothing like being able to come home and work."
“I just thought it would be fun and I love working on Australian projects and working here in general,” she said.
“And Jason Perini (director) is taking a really unique spin on a footy film with a very artistic take on it, which I find exciting.”
Speaking of her character, she mused, “Brooke has strong values and she is learning to stand up for herself and what she deserves and doesn’t deserve in terms of a partnership and she sort of helps Dan Ewing’s character to look at his own values and the way he treats women.”
Isabel became a household name after starring in Home and Away as Tasha Andrews, opposite Chris Hemsworth.
Chasing Comets is expected to be in cinemas in spring.