But the 47-year-old couldn't help but speak openly and honestly when a young jury member at the 46th Annual Giffoni Film Festival asked the starlet if she ever woke up in the morning and questioned who she was.
Watch how the seemingly innocent question brought Jen to tears in the video player below... Post continues!
"Yes, that moment has happened to me. There's not enough fingers and toes in this entire room to count how many times that moment has happened," a visibly moved Jen responded.
"We're all human beings at the end of the day, whether we're a waitress or we're a baker or we're a student – whatever we are, at the end of the day, you can kind of hit walls and think 'I can't go any farther.' Or 'this is too much, my heart can't take it.' Or 'the pain is too great.' Or 'am I good enough?'Oor, 'Will I survive?'"
Adding, "And you just have to sort of, somehow, miraculously overcome. You just go, 'I can.' Yes, you can."
Her incredible response brought the entire auditorium to their feet, as all the teens in room had a moment of mutual understanding with the Hollywood superstar.
Jennifer, who married Justin Theroux last year, was caught off guard by the question, but it was clear the profound words resonated with her.
Addressing the kids, she reinforced her views on insecurities.
"Also know that your actors, your idols, your icons – whatever you call them – have all had that experience or that moment in their lives, many many times," she mused.
Watch Jen's hubby speak fondly about their love in the video below! Post continues...
"There's nothing that separates us from you because we all started at the same place," she said.
"We all came out of nowhere... don't punish yourself, if you feel that."
The beloved TV icon has always been a figure for empowerment and standing up for yourself.
She famously once mused to Diana Sawyer, "I think once you figure out who you are and what you love about yourself, I think it all kind of falls into place."