Isabella, 8, and her 5-year-old brother Conner hold mum Nicole Kidman's hand on a windy day out in New York.
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Tom attentively watches over Isabella at a family picnic.
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Despite Nicole and Tom's 2001 divorce, both parents made sure they had plenty of time for their pre-teen children, both of whom were adopted as infants.
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Isabella rides alongside her aunt, Antonia, and young cousin on the way to Nicole's 2006 wedding to Keith Urban.
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When Tom started dating Katie Holmes, Isabella's stepmother-to-be was a constant presence at her weekend soccer games.
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Baby Suri was born in April 2006, just one year after Katie and Tom married - making Isabella a big sister for the second time. Though there have never been reports of animosity in the Cruise-Holmes clan, little Suri demands much of her parents' time.
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As TomKat gained momentum with paparazzi around the world, Connor and Isabella were often caught lingering in the background of family snaps.
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Isabella was regularly snapped with her dad as she blossomed into a young woman, but where is she now?