Beginning the night with an impassioned opening speech, presenter Ashton Kutcher slammed Donald Trump's anti-immigration policies. The actor welcomed the audience and “everyone in airports that belong in my America!”
"You are a part of the fabric of who we are, and we love you, and we welcome you," he continued as the crowd erupted in support.
The sentiment was echoed by the first winner of the night, Julia Louis-Dreyfus, who also used her time on the stage to question Trump's "un-American" stance.
"I want you all to know that I am the daughter of an immigrant,” the Veep actress began.
“My father fled religious persecution in Nazi-occupied France and I’m an American patriot and I love this country. Because I love this country, I am horrified by its blemishes and this immigrant ban is a blemish and it is un-American.”
Emma Stone scored the Outstanding Performance by a Female Actor in a Leading Role in La La Land and thanked her co-star Ryan Gosling.
"Ryan, you're the best. That's just the truth. No one can argue it," Emma said.
"I feel insecure a lot of the time, genuinely. Feeling like I could deserve anything like this requires a bit of mental gymnastics for me," Emma confessed.
Best Actor winner Denzel Washington also admitted his nerves. "We're just actors. I'm famous and all that kind of stuff, but i have the same fear, opening night, first preview."
"I'm a God-fearing man, I'm supposed to have faith, but I didn't have faith. I'm getting choked up," he confessed of not having pre-prepared his speech.
Meanwhile Dolly Parton brought the top notch banter as she introduced her dear friend Lily Tomlin, who was awarded receiving the Lifetime Achievement Award.
"Greetings from Dollywood, Hollywood. I think it was IDs [they were checking backstage], maybe it was Double Ds. Glad to get that off my chest," she quipped of her bust.
Keep scrolling for all the winners and grinners from tonight!
Outstanding Performance by a Cast in a Motion Picture
WINNER: Hidden Figures
Manchester by the Sea
Outstanding Performance by a Male Actor in a Leading Role
Casey Affleck, Manchester by the Sea
Andrew Garfield, Hacksaw Ridge
Ryan Gosling, La La Land
Viggo Mortensen, Captain Fantastic
WINNER: Denzel Washington, Fences
Outstanding Performance by a Female Actor in a Leading Role
Amy Adams, Arrival
Emily Blunt, The Girl on the Train
Natalie Portman, Jackie
WINNER: Emma Stone, La La Land
Meryl Streep, Florence Foster Jenkins
Outstanding Performance by a Male Actor in a Supporting Role
WINNER: Mahershala Ali, Moonlight
Jeff Bridges, Hell or High Water
Hugh Grant, Florence Foster Jenkins
Lucas Hedges, Manchester by the Sea
Dev Patel, Lion
Outstanding Performance by a Female Actor in a Supporting Role
WINNER: Viola Davis, Fences
Naomie Harris, Moonlight
Nicole Kidman, Lion
Octavia Spencer, Hidden Figures
Michelle Williams, Manchester by the Sea
Outstanding Performance by a Stunt Ensemble in a Motion Picture
Captain America: Civil War
WINNER: Hacksaw Ridge
Outstanding Performance by an Ensemble in a Drama Series
Game of Thrones
WINNER: Stranger Things
Outstanding Performance by an Ensemble in a Comedy Series
The Big Bang Theory
WINNER: Orange Is the New Black
Outstanding Performance by a Male Actor in a Drama Series
Sterling K. Brown, This Is Us
Peter Dinklage, Game of Thrones
WINNER: John Lithgow, The Crown
Rami Malek, Mr. Robot
Kevin Spacey, House of Cards
Outstanding Performance by a Female Actor in a Drama Series
Millie Bobby Brown, Stranger Things
WINNER: Claire Foy, The Crown
Thandie Newton, Westworld
Winona Ryder, Stranger Things
Robin Wright, House of Cards
Outstanding Performance by a Male Actor in a Comedy Series
Anthony Anderson, Black-ish
Tituss Burgess, Unbreakable Kimmy Schmidt
Ty Burrell, Modern Family
WINNER: William H. Macy, Shameless
Jeffrey Tambor, Transparent
Outstanding Performance by a Female Actor in a Comedy Series
Uzo Aduba, Orange Is the New Black
Jane Fonda, Grace and Frankie
Ellie Kemper, Unbreakable Kimmy Schmidt
WINNER: Julia Louis-Dreyfus, Veep
Lily Tomlin, Grace and Frankie
Outstanding Performance by a Female Actor in a TV Movie or Miniseries
Bryce Dallas Howard, Black Mirror
Felicity Huffman, American Crime
Audra McDonald, Lady Day at Emerson’s Bar and Grill
WINNER: Sarah Paulson, The People vs. O.J. Simpson: American Crime Story
Kerry Washington, Confirmation
Outstanding Performance by a Male Actor in a Miniseries or Television Movie
Riz Ahmed, The Night Of
Sterling K. Brown, The People vs. O.J. Simpson: American Crime Story
WINNER: Bryan Cranston, All the Way
John Turturro, The Night Of
Courtney B. Vance, The People vs. O.J. Simpson: American Crime Story